Publications

  • Kasinath, V*, Poepsel, S*, and Nogales, E. 2019. Recent Structural Insights into Polycomb Repressive Complex 2 Regulation and Substrate Binding (REVIEW)Biochemistry. 58(5):346-354. 
  • Poepsel, S, Kasinath, V and Nogales, E. 2018. Cryo-EM structures of PRC2 simultaneously engaged with two functionally distinct nucleosomes. Nature Structural & Molecular Biology. 25, 154-162. 
  • Kasinath, V., Faini, M., Poepsel, S., Reif, D., Feng X.A., Stjepanovic, G., Aebersold, R. and Nogales, E. 2018. Structures of human PRC2 with its cofactors AEBP2 and JARID2. Science. 359: 940-944. 
  • Kellogg, E.H., Hejab, N., Poepsel, S., Downing, K.H., DiMaio, F., Nogales, E. 2018. Near-atomic model of microtubule-tau interactions. Science. 360(6394):1242-1246. 
  • Poepsel, S., Sprengel, A., Sacca, B., Kaschani, F., Kaiser, M., Gatsogiannis, C., Raunser, S., Clausen, T., Ehrmann, M.: Determinants of amyloid fibril degradation by the PDZ protease HTRA1. Nature Chemial Biology. 11: 862-9. 
  • *Tennstaedt, A., *Popsel, S., Truebestein, L., et al. 2012. Human High Temperature Requirement Serine Protease A1 (HTRA1) Degrades Tau Protein Aggregates. Journal of Biological Chemistry 287: 20931-20941.
  • *Merdanovic, M., *Mamant, N., *Meltzer, M., *Poepsel, S., Auckenthaler, A., Melgaard, R., et al. 2010. Determinants of structural and functional plasticity of a widely conserved protease chaperone complex. Nature Structural & Molecular Biology. 17: 837-843.